Throughout the early Congresses, participants prided themselves on not being a formally codified gathering only for the purpose of scientific exchange. Although this formula was relatively successful in the past, it increasingly became evident that lack of a formal organisation hampered local organisers. In 1994 at the Jerusalem Congress, it was decided to establish formally an International Society. The goal continued to be fostering international exchange in prenatal genetic diagnosis through governance of a society that was international and multidisciplinary democratic in nature.
The initial officers were selected by the Scientific Advisory Committee of the Goa Congress and directed to proceed with its organisation. These officers were Joe Leigh Simpson (USA), President; Haim Zakut (Israel), Secretary; Henri Goldstein (Denmark), Treasurer. Initial Board members were Bruno Brambati (Italy), Malcolm Ferguson-Smith (UK), Enrique Gadow.
With support from the March of Dimes in the United States, by-laws and documentation were prepared and the Society formally registered in the United States (Illinois) in 1996. The Board of Directors now holds quarterly teleconferences, in addition to meeting in person at the now annual International Conference.
In 2005, ISPD contracted with its association management company, Custom Management Group, located in Charlottesville, Virginia, USA. This provided the Society with an Executive Director, a Program Director, a Director of Website Services, a Manager of Membership Services and customer support services via telephone and e-mail. Please see the Contact page for address, phone and e-mail information.
In 2012, ISPD opened membership to all those who were prior members of the International Prenatal Screening Group, which gave them automatic membership in our Prenatal Maternal Screening Specialty Interest Group (SIG). ISPD incorporated their popular newsletter into the SIG section of the ISPD owned newsletter: Prenatal Perspectives, which was first distributed in 2013 and is published online quarterly to the ISPD membership.